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Percocet contains a blend of acetaminophen and oxycodone. Oxycodone is a narcotic agony medicine. A narcotic is at times called an opiate. Acetaminophen is a less intense agony reliever that expands the impacts of oxycodone. Percocet is utilized to calm moderate to extreme agony. Due of the danger

Important Dosage and Administration Instructions

Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals

Initiate the dosing regimen for each patient individually, taking into account the patient’s severity of pain, patient response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse

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Monitor patients closely for respiratory depression, especially within the first 24 to 72 hours of initiating therapy and following dosage increases with PERCOCET and adjust the dosage accordingly

Initial Dosage

Initiating Treatment with PERCOCET

Initiate treatment with PERCOCET tablets 2.5 mg/325 mg adult dosage, with one or 2 tablets every 6 hours as needed for pain. The total daily dose of acetaminophen should not exceed 4 grams.

The usual adult dosage is one tablet every 6 hours as needed for pain. The total daily dose of acetaminophen should not exceed 4 grams.

StrengthUsual Adult DosageMaximal
Daily Dose
PERCOCET 2.5 mg/325 mg1 or 2 tablets every 6 hours as neededfor pain12 Tablets
PERCOCET 5 mg/325 mg1 tablet every 6 hours as needed for pain12 Tablets
PERCOCET 7.5 mg/325 mg1 tablet every 6 hours as needed for pain8 Tablets
PERCOCET 10 mg/325 mg1 tablet every 6 hours as needed for pain6 Tablets

Conversion from Oxycodone Hydrochloride and Acetaminophen to Extended-Release Oxycodone

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The relative bioavailability of Oxycodone Hydrochloride and Acetaminophen Tablets or Oral Solution compared to extended-release oxycodone is unknown, so conversion to extended-release oxycodone must be accompanied by close observation for signs of excessive sedation and respiratory depression.

Titration and Maintenance of Therapy

Individually titrate PERCOCET to a dose that provides adequate analgesia and minimizes adverse reactions. Continually reevaluate patients receiving PERCOCET to assess the maintenance of pain control and the relative incidence of adverse reactions, as well as monitoring for the development of addiction, abuse, or misuse . Frequent communication is important among the prescriber, other members of the healthcare team, the patient, and the caregiver/family during periods of changing analgesic requirements, including initial titration.

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If the level of pain increases after dosage stabilization, attempt to identify the source of increased pain before increasing the PERCOCET dosage. If unacceptable opioid-related adverse reactions are observed, consider reducing the dosage. Adjust the dosage to obtain an appropriate balance between management of pain and opioid-related adverse reactions.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Related questions


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