What is OxyContin (10mg, 20mg, 40mg, 60mg, 80mg)?
OxyContin (oxycodone) is an opioid pain medication, sometimes called narcotic. OxyContin is a strong prescription medicine that is used when an opioid medication requires sufficient time to control severe pain to require prolonged daily treatment with an opioid when other pain treatments, Such as non-opioid analgesics or immediate release opioid medications do not treat your pain well or cannot tolerate them.
Not 24 hours that OxyContin should not be used as needed for pain.
Precautions for use Oxycontin 40mg
The greatest risk of opioid overdose is respiratory depression. Caution should be exercised when administering oxycodoneto weakened elderly; Patients with severe pulmonary insufficiency, patients with hepatic or renal insufficiency; myxedema, hypothyroidism, Addison’s disease, toxic psychosis, prostate hypertrophy, adrenocortical insufficiency, alcoholism, delirium, biliary tract diseases, pancreatitis, inflammatory bowel disorders, hypovascularia, increased intracranial pressure, head injury (due to risk ), increased intracranial pressure) Or patients taking benzodiazepines, other CNS depressants (including alcohol) or MAO inhibitors.
Concomitant use of benzodiazepines and opioids can cause syncope,Respiratory depression, coma and death. Because of these risks, the prescription of medications related to concomitant medications, such as benzodiazepines or opioids, should be reserved for patients for whom alternative treatment options are not possible.
If it is decided to prescribe benzodiazepines with opioids, the lowest effective dose should be used and the duration of treatment should be as short as possible.
Patients should be closely monitored for signs and symptoms of respiratory depression and depression. In this regard, it is strongly recommended to inform patients and their environment so that they are aware of these symptoms.
OxyContin tablets should not be used where there is a possibility of paralytic ileus. If paralytic ileus is suspected or may occur during use, OxyContin Tablet should be discontinued immediately. OxyCodone tablets are not recommended for preoperative use within the first 12–24 hours after the operation.
As with all opioid preparations, oxycodone products should be used with caution after abdominal surgery, as it is known that opioids disrupt intestinal motility and should not be used unless the doctor Not sure about normal bowel function.
Patients undergoing additional procedures for pain relief (eg, surgery, plexus block) should not receive OxyContin Pills for 12 hours prior to intervention. If additional treatment with OxyContin tablets is indicated, the dose should be adjusted for the new postoperative requirement.
OxyContin 60Mg tablets should not be used in patients who were not previously exposed to opioids. When administered to patients without prior opioid treatment, concentrations of these pills can cause fatal respiratory depression.
When administered to patients without prior treatment of opioids, OxyContin 80 mg can cause fatal respiratory depression.
OxyContin 80mg tablets should not be used in patients who have not been previously exposed to opioids. The potency of this tablet can cause fatal respiratory depression when given to patients without prior opioid treatment.
For appropriate patients suffering from chronic non-fatal pain, opioids should be used as part of a comprehensive treatment program that includes other medications and treatment modalities. An important part of the evaluation of a patient with chronic non-fatal pain is the patient’s history of addiction and substance abuse.
If opioid treatment is considered appropriate for the patient, the main goal of treatment is not to reduce the opioid dose, but to achieve a dose that provides adequate pain relief with minimal side effects. There should be frequent contact between the doctor and the patient so that dose adjustments can be made. It is strongly recommended that the physician define treatment outcomes according to pain management guidelines. Doctors and patients can agree to discontinue treatment if these goals are not met.
The patient may develop tolerance to medication with chronic medication and require progressively higher doses to maintain pain control. Prolonged use of this product may cause physical dependence and symptoms may return when therapy is abruptly discontinued. When a patient no longer needs oxycodone therapy, it may be advisable to reduce the dose gradually to prevent withdrawal symptoms. Opioid withdrawal or withdrawal syndrome is characterized by some or all of the following symptoms: restlessness, tearing, rhinorrhea, yawning, sweating, chills, myalgia, mydriasis and palpitations. Other symptoms may also develop, including: irritability, anxiety, back pain, joint pain, weakness, abdominal cramps, insomnia, nausea, anorexia, vomiting, diarrhea or increased blood pressure, respiratory rate or heart rate.
There may be hyperlugesia that will not respond to additional increases in oxycodone doses, especially at higher doses. A reduction in the dose of oxycodone or a change in alternative opioids may be necessary.
Oxycodone has an abuse profile similar to other strong opioids.Buy Oxycodone online no prescription can be sought and abused by people with latent or extreme intoxication disorders. There is a possibility of developing psychological dependence [addiction] for opioid analgesics, including oxyodone.OxyContin side effect should be used with special care in patients with a history of alcohol and drug abuse.
Like other opioids, children born to dependent mothers may have withdrawal symptoms and respiratory depression at birth.
OxyContin tablets should be swallowed whole, and should not be broken, chewed, or crushed. Administration of broken, chewed or crushed OxyContin tablets leads to rapid release and absorption of lethal doses of oxycodone .
Concomitant use of alcohol and OxyContin may increase undesirable effects of OxyContin ; Concomitant use should be avoided.
Abuse of oral dosage forms by peripheral administration is expected to cause serious adverse events, such as increased risk of local tissue necrosis, infection, pulmonary granuloma, endocarditis, and valvular heart injury, which can be fatal. May go.
You can see an empty matrix (tablet) in the stool.
Acute hypertrophy with oxycodone can be manifested by myosis, respiratory depression, hypotension and hallucinations. The progress of stupa or coma, hypotonia, bradycardia, pulmonary edema and deepening may occur in more severe cases due to circulatory failure and syncope.
The simultaneous ingestion of alcohol or other psychotropic drugs will enhance the effects of an overdose.
Treatment of oxycodone excess: primary attention should be given to the establishment of a patented airway and the establishment of assisted or controlled ventilation. Pure opioid antagonists such as naloxone are specific antidotes against the symptoms of opioid overdose. Other supportive measures should be employed as necessary.
In case of massive overdose, if the patient is in a coma or respiratory depression, administer naloxone (0.4 to 2 mg and 0.01 mg / kg body weight for children) to an adult. If there is no response, repeat the dose in an interval of 2 minutes. An infusion of 60% of the initial dose per hour is a useful starting point if repeated doses are required. A 10 mg solution, made in 50 ml of dextrose, would produce 200 μg / ml for infusion using an IV pump (dose adjusted for clinical response). Infection is not an option for repeated review of the patient’s clinical condition. Intramuscular naloxone is an option if IV access is not possible. Since the duration of the action of naloxone is relatively short, the patient should be carefully monitored until spontaneous breathing is reliably restored. Naloxone is a competitive antagonist and may require higher doses (4 mg) in severely poisoned patients.
For a less severe overdose, administer naloxone 0.2 mg followed by an increase of 0.1 mg every 2 minutes if necessary.
The patient should be observed for at least 6 hours after the last dose of naloxone.
OxyContin should not be administered in the absence of clinically significant respiratory or circulatory depression for oxycodone overdose. Naloxone should be administered with caution to those known or suspected to be physically dependent on oxycodone. In such cases, a sudden or complete reversal of opioid effects can cause pain and an acute withdrawal syndrome.
Additional / other considerations
• Consider activated carbon (50 grams for adults, 10-15 grams for children) if ingested in sufficient quantities within 1 hour, provided that the airways are protected. It may be reasonable to assume that late administration of activated carbon may be beneficial for long-term release preparations; However, there is no evidence to support this.
• OxyContin will continue to release and add to the oxycodone charge for up to 12 hours after administration of the tablet and the management of oxycodone overdose should be modified accordingly. Therefore, it may be necessary to empty the gastric content since this may be useful for removing the unbaked drug, especially when an extended-release formulation has been taken.2 views